Which two signs are commonly seen together in MG?

Which two signs are commonly seen together in MG?

• A. Ptosis and diplopia
• B. Nystagmus and vertigo
• C. Tinnitus and hearing loss
• D. Dysphagia and urinary retention

Answer: (A)

In myasthenia gravis, weakness stems from impaired signaling at the neuromuscular junction, and the eye muscles are affected very early. When the extraocular muscles become weak, you see ptosis (drooping eyelids) and diplopia (double vision). These two signs tend to appear together because they both arise from the same susceptible eye muscle group. The other option pairs describe problems from different systems (vestibular/inner ear, auditory system, or nonocular muscles with urinary symptoms) and aren’t the classic combination seen with MG.

In myasthenia gravis, weakness stems from impaired signaling at the neuromuscular junction, and the eye muscles are affected very early. When the extraocular muscles become weak, you see ptosis (drooping eyelids) and diplopia (double vision). These two signs tend to appear together because they both arise from the same susceptible eye muscle group. The other option pairs describe problems from different systems (vestibular/inner ear, auditory system, or nonocular muscles with urinary symptoms) and aren’t the classic combination seen with MG.